Huperzine A

Abstract

Huperzine A is extracted from Huperzia serrata.It is a reversible acetylcholinesterase     inhibitor and NMDA receptor antagonist that crosses the blood-brain barrier.The structure of the complex of huperzine A with acetylcholinesterase has been determined by X-ray crystallography .

For some years, huperzine A has been investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer's disease. A 2013 meta-analysis found that huperzine A may be efficacious in improving cognitive function, global clinical status, and activities of daily living for individuals with Alzheimer’s disease. However, due to the poor size and quality of the clinical trials reviewed, huperzine A should not be recommended as a treatment for Alzheimer’s disease until further high quality studies confirm its beneficial effects.

Huperzine A is also marketed as a dietary supplement with claims made for its ability to improve memory and mental function. Huperzine A may also have a possible role in the treatment of myasthenia gravis.


Specifications

Huperzine A 1%,98%.

Synthetic Huperzine A  99%.


Functions

1. Enhance cognition, improve memory;

2. Contribute to restore short-term memory damage, slow brain aging;

3. Treat age-related memory loss and Alzheimer's disease;

4. Treat Myasthenia gravis.


What are Health Benefits

Huperzine is a standardized extract from the Chinese club moss is an all-natural herbal supplement that may help prevent the breakdown of acetylcholine. Huperzine's action has been attributed to its ability to strongly inhibit acetylcholinesterase, the enzyme that breaks down acetylcholine in the synaptic cleft. Acetylcholine is involved in memory and learning. Huperzine A has also been found to be beneficial in patients with Alzheimer’s disease. Huperzine A had improvements in memory, cognition, and behavioral functions whereas only 36 percent of those on placebo improved. No severe side effects were found. Blood pressure, heart rate, electrocardiogram, electroencephalogram, liver and urine tests did not show any major abnormalities. The researchers say, "Huperzine A is a promising drug for symptomatic treatment of Alzheimer's disease."


Congeneric Product

1. Alpha GPC

2. Pyrroloquinoline Quinone Disodium Salt(PQQ)

3. Adrafinil

4. Vinpocetine

5. Phosphatidic Acid

6. Sialic acid

7. Arachidonic Acid

8. Phosphatidylserine

9. Phosphatidylcholine

10. Cordycepin

11. Galantamine HBr

12. Noopept

13. N-Methyl-D-Aspartic Acid

14. Magnesium L-threonate

15. Gastrodin

16. Pramiracetam

17. Bacopa Extract (10%~50%)

18.Oxiracetam

19. Citicoline

20. Coluracetam

21.PRL-8-53

22.NSI-189

23. Fasoracetam